The fire erupted around 5:30 a.m. at a home in the 900 block of Summit Avenue in Schwenksville, Pa.
"Our office is devastated to learn about this tragedy," said Montgomery County Sheriff Sean P. Kilkenny said in a statement. "Our thoughts and prayers are with the Lukens family as they grieve their losses."
The blaze was placed under control shortly after fire crews arrived, police say.
Fire marshals are working to determine a cause of the fire.
By Wednesday night, crews were boarding up a home that was once filled with an active family.
"Very energetic, always doing something, always at the basketballs courts and everything, boys were always out playing," said neighbor Lisa Dull.
Those who know the family are stunned by this tragedy.
"I can't imagine losing one child, let alone two and knowing you did everything you could to save them," said family friend Kyle Boelter. "I don't know how they move on. We as a community have to rally around them."
A makeshift memorial began to grow Wednesday night outside of a security fence placed around the property.
"I just can't believe it," said family friend Mary McGill. "It's worse than I thought."
Officials have not released any word as to the cause of the fire; the investigation is ongoing.
This news has been published by title 2 Sons Of Montgomery Co. Deputy Perish In Schwenksville, Pa. Fire
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